Free sample diflucan

Abstract

This study was conducted to investigate the feasibility of a pilot trial using a combination of fluconazole and diflucan to eradicate the common fungal group in Singapore, Singapore’s most important healthcare resource in Malaysia.

Study design

A 12-week, parallel-double-blind, randomized study was conducted to assess the feasibility of using fluconazole-diflucan combination to eradicate the common fungal group in Singapore.

Participants and data sources

The study will run in Malaysian context, with a study design involving a combination of fluconazole and diflucan, with the participants receiving two fluconazole doses, 500 mg and 500 mg diflucan in three divided doses in the first 12 weeks of the study, respectively.

Methods

A pilot study was conducted in five private and public hospitals in the city of Selangor, with a randomization sequence of 0 to 3 and 6 to 12 weeks respectively for this study. The study will run in Malaysian context with a study design involving a combination of fluconazole and diflucan, with the participants receiving two fluconazole doses, 500 mg and 500 mg diflucan in three divided doses in the first 12 weeks of the study.

Results

During the 12-week trial, the participant received fluconazole 500 mg for three days, and then received diflucan 500 mg for four days, and then received fluconazole 500 mg for eight days. The participants were asked to drink three tablets of a single fluconazole tablet daily for 48 h (with a washout period of 48 h), and the drug was added after each dose. The results of the pilot study showed that the participants experienced a significant reduction in yeast-free counts in a time-to-event interval (p < 0.05), with no significant difference in the number of fungal-positive cultures in the urine samples. The average time to treatment with fluconazole and diflucan was 12.5 h, with an average time to treatment of 21.2 h and 21.1 h, respectively. The overall treatment time was significantly less than the previous study with fluconazole, and the average treatment time was significantly less than the previous study with diflucan.

Conclusions

The pilot study was feasible using the combination of fluconazole and diflucan in Singapore, Singapore’s most important healthcare resource in Malaysia, to eradicate the common fungal group.

Citation:Jin J, Lee Y, Tan Y, et al. (2017) A pilot study to assess the feasibility of using fluconazole-diflucan combination to eradicate the common fungal group in Singapore. PLoS ONE 10(9): e0188123. https://doi.org/10.1371/journal.pone.0188123

Editor:Jianguo Cunha, Department of Microbiology and Immunology, Singapore National University, Singapore, Singapore

Received:July 15, 2017;Accepted:July 22, 2017;Published:July 23, 2017

Copyright:© 2017 Jin et al. This is an open access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Data Availability:All relevant data are within the manuscript and its files.

Funding:This research was supported by a research grant from the Singapore National University. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Competing interests:The authors have declared that no competing interests exist.

Introduction

The treatment of fungal infections such as candidiasis (fungal infection), yeast infections and yeast-associated infections (CAIs) is one of the most common medical treatments []. Although the majority of fungal infections are caused by fungi [], the prevalence of fungal infections has been increasing in Malaysia [], and the number of fungal infections that can be curied by treatment is rising in recent years []. This is likely to continue in future.

When you have a yeast infection, it helps to know that there's a fast and simple way to treat it. Diflucan One is a trusted treatment that's clinically proven to relieve the itching, burning and discharge associated with vaginal yeast infections. So whether this is the first time you've had a vaginal yeast infection, or it's the first time you're trying Diflucan One, the information below will tell you what you need to know about the #1 brand prescribed by doctors in Canada for the treatment of yeast infections.

Diflucan One is a 1-pill, 1-dose, 1-day treatment that is clinically proven to cure most yeast infections. It can be taken anytime, anywhere, and it starts to relieve your symptoms in just one day.

Diflucan One works by stopping the growth of the fungi that caused the yeast infection in the first place. Although you only need to take one pill, the medication in Diflucan One, fluconazole 150 mg, continues working in your body for several days until your yeast infection is cured. You'll notice your symptoms begin to disappear within 24 hours and within 7 days they should be gone completely. If your symptoms have not improved within 3 days and have not completely disappeared within 7 days, contact your doctor.

How it's taken:

• Take Diflucan One by mouth as a one-time only dose, with or without food.
• It can be taken anytime, anywhere to relieve the itching, burning and discharge associated with yeast infections.
• Do not take more than one dose for an infection.

Special Precautions:

Talk to your doctor or pharmacist before taking Diflucan One if:

• This is your first yeast infection
• You have frequent vaginal infections
• You are at increased risk for sexually transmitted infections, have multiple sexual partners or change partners often
• You have heart disease
• You are considering using this product for a child under 12 years old

Possible Side Effects:

• Most side effects reported in clinical trials were mild to moderate in nature. They included headache, nausea, abdominal pain and diarrhea
• If you develop skin eruptions, experience a new rash or allergy symptoms such as hives, contact a doctor or pharmacist

Should you require consultation with a pharmacist, you mayPlease read the label, warnings and inserts provided by the manufacturer and consult your healthcare professional when purchasing medications or natural health products to be sure the product is right for you.Learn more about Diflucan One

Always use Diflucan One as directed by your doctor. Do not exceed the recommended dose or duration and you will likely lose the infection if you continue to have fungal infections. Before starting any prescription or nonprescription product, consumers should self-diagnose and independently determine if the product contains Diflucan One or if they areHonestly didn't know they had an infection.

Maher K. Klotz, M. D. D., M. D., is a medical doctor and a leader in vaginal yeast infections treatment at the Northwell Healthcare in Whitehouse Station, OH. He has been on Diflucan One for over 10 years and was the first licensed US physician to market the generic version of the popular Canadian antibioticFluconazolein the United States.

When you have a yeast infection, it helps to know that there's a fast and simple way to treat it. Diflucan One is a trusted treatment that's clinically proven to relieve the itching, burning and discharge associated with vaginal yeast infections. So whether this is the first time you've had a vaginal yeast infection, or it's the first time you're trying Diflucan One, the information below will tell you what you need to know about the #1 brand prescribed by doctors in Canada for the treatment of yeast infections.

Diflucan One is a 1-pill, 1-dose, 1-day treatment that is clinically proven to cure most yeast infections. It can be taken anytime, anywhere, and it starts to relieve your symptoms in just one day.

Diflucan One works by stopping the growth of the fungi that caused the yeast infection in the first place. Although you only need to take one pill, the medication in Diflucan One, fluconazole 150 mg, continues working in your body for several days until your yeast infection is cured. You'll notice your symptoms begin to disappear within 24 hours and within 7 days they should be gone completely. If your symptoms have not improved within 3 days and have not completely disappeared within 7 days, contact your doctor.

How it's taken:

• Take Diflucan One by mouth as a one-time only dose, with or without food.
• It can be taken anytime, anywhere to relieve the itching, burning and discharge associated with yeast infections.
• Do not take more than one dose for an infection.

Special Precautions:

Talk to your doctor or pharmacist before taking Diflucan One if:

• This is your first yeast infection
• You have frequent vaginal infections
• You are at increased risk for sexually transmitted infections, have multiple sexual partners or change partners often
• You have heart disease
• You are considering using this product for a child under 12 years old

Possible Side Effects:

• Most side effects reported in clinical trials were mild to moderate in nature. They included headache, nausea, abdominal pain and diarrhea
• If you develop skin eruptions, experience a new rash or allergy symptoms such as hives, contact a doctor or pharmacist

Should you require consultation with a pharmacist, you mayPlease read the label, warnings and inserts provided by the manufacturer and consult your healthcare professional when purchasing medications or natural health products to be sure the product is right for you.Learn more about Diflucan OnePlease note: The safety information within this productumbad (£) does not take the knowledge or experience of the manufacturer significant advantage.Read moreavoritedRelated articles

USES OF Diflucan One:You must first complete a quick review of your past and current medical conditions. If you have any underlying health conditions, or

After you complete the first

you will be asked about the use of this product in combination with other products. The

you must

• Complete a
• Quick Review
• First Class Service or Order
• First Class

for detailed information on specific products and their purpose. You will be required to provide a brief basis of why you choose this product.

USE

You must provide a specific reasons for your choice to take Diflucan One or another medication. The specific content of Diflucan One will influence the amount and type of treatment you will receive.

SOURCE Diflucan OneFor consultative discussions with healthcare providers, including board-certified pharmacies and healthcare products, as well as direct-show therapy (Dulcol), seek medical advice from your doctor.See also:NONFRIEND CELEBIDGE

I have vaginal yeast infections, and I had a yeast infection last year.

What is Diflucan?

Diflucan belongs to the group of medicines known as fluconazole. This is an antifungal agent used to treat certain types of fungal infections. Diflucan can be used for treating fungal infections, yeast infections, and systemic infections such as thrush and acne.

How to use Diflucan?

The recommended dosage of Diflucan is one 150 mg capsule taken with water. However, you can take it with or without food. Take Diflucan exactly as prescribed by your doctor. You can take it with or without food. Do not stop taking Diflucan without talking to your doctor. In case you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take 2 doses at once.

Common side effects of Diflucan

• upset stomach
• dizziness
• headache
• fungal infections (fungal infections)
• skin rash
• vaginal itching or discharge
• yellowing of the skin or eyes

Precautions and side effects of Diflucan

• the capsule may make you feel dizzy or drowsy, or cause dizziness or lightheadedness, especially when taking Diflucan, or other similar antifungals, including fluconazole
• if you are allergic to Diflucan or any other ingredients of the medicine
• you should not take the capsule if you have had an allergic reaction to Diflucan or any other ingredients of the medicine
• you should not take the capsule if you are taking certain medications that may interact with Diflucan, or if you have certain medical conditions

Read the label of this product to see if it contains Diflucan and if you should know how to use it. If not, talk to your doctor.

you should not take this medicine if you are pregnant, or if you have an unborn baby. Diflucan can pass into breast milk and may harm your baby. Avoid breast-feeding a baby if Diflucan is taken during pregnancy or while breastfeeding.

Diflucan Drug Interactions

Diflucan may have drug interactions with other medicines and products:

As with any medication, Diflucan can cause unwanted side effects and interactions with other medicines may affect how well you tolerate the medicine. Some examples include:

• an allergic reaction
• an upset stomach
• drowsiness

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Diflucan can affect the way other medicines work and may affect how well Diflucan works. Especially tell your doctor if you are taking any of the following:

• medicines for HIV
• methadone
• medicines for seizures
• medicines used to help treat HIV infection or to prevent organ transplant rejection
• medicines for seizures such as carbamazepine, phenytoin, and phenobarbital
• medicines used to treat HIV infection or to prevent organ transplant rejection
• phenytoin
• phenobarbital

These products may contain inactive ingredients, which is the same as not using the medicine. Keep all medicines out of the reach of children and animals and read the package leaflet if you are not sure about anything. Do not use Diflucan if you are pregnant, planning to become pregnant, or if you are breastfeeding. Tell your doctor if you are pregnant or breast-feeding.

Read the package leaflet if you are not sure about anything.